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Table 1 Symptom-lesion mapping of the vestibulo-cerebellar syndrome

From: Schmahmann’s syndrome - identification of the third cornerstone of clinical ataxiology

Area involved

Symptom

Oculomotor vermis

Hypometric saccades

Impaired smooth pursuit

Fastigial nucleus

Square waves

Hypermetric saccades

Impaired smooth pursuit

Saccadic oscillations

Nodulus/uvula

Nystagmus (DBN1, PAN2)

Skew deviation

Flocculus/paraflocculus

Nystagmus (DBN1, GEN3)

Impaired smooth pursuit

Impaired VOR4

  1. Abbreviations: 1 DBN down-beat nystagmus, 2 PAN periodic alternating nystagmus, 3 GEN gaze-evoked nystagmus, 4 VOR vestibulo-ocular response.