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Table 2 Summary of serological and histopathological characteristics of the 9 patients

From: Myoclonus ataxia and refractory coeliac disease

Case Age/sex Gluten related antibodies baseline Gluten related antibodies on strict gluten-free diet Duodenal biopsy baseline Duodenal biopsy on diet (duration on diet in years)
   EMA TG2 AGA TG6 EMA TG2 AGA TG6   
1 50/M n/a n/a n/a n/a -ve -ve -ve -ve Enteropathy Enteropathy (10), EAL
2 60/F +ve n/a +ve IgG pos -ve -ve -ve -ve Enteropathy Enteropathy (5), type 1
3 63/M +ve +ve +ve IgG, IgA pos -ve -ve -ve -ve Enteropathy Enteropathy (3), type 1
4 53/M n/a n/a n/a n/a -ve -ve -ve -ve Enteropathy Enteropathy (10), type 2
5 76/M +ve +ve +ve IgA pos -ve -ve -ve -ve Enteropathy Enteropathy (2), type 1
6 46/F +ve +ve n/a n/a +ve -ve +ve IgG -ve Enteropathy Enteropathy (2), type 1
7 61/M +ve +ve +ve IgG, IgA n/a -ve +ve +ve IgG -ve Enteropathy Enteropathy (1), type 1
8 52/F -ve +ve +ve IgG, IgA pos -ve +ve +ve IgG,IgA -ve Enteropathy Enteropathy (1), type 1
9 74/M +ve +ve n/a n/a -ve -ve +IgA -ve Enteropathy Enteropathy (1.5), type 1
  1. EMA = endomysium antibodies.TG2 = transglutaminase antibodies type 2. AGA = antigliadin antibodies. TG6 = transglutaminase antibodies type 6. EAL = enteropathy associated lymphoma. Enteropathy = triad of villous atrophy, crypt hyperplasia and increased intraepithelial lymphocytes. Type 1 enteropathy = refractory enteropathy. Type 2 enteropathy = refractory enteropathy with abnormal intraepithelial T cells.