Figure 1

Highest differences between patients with SCA7 and healthy controls. Nodes represent the AAL regions involved in each of 19 abnormal functional connections. Node color indicates the anatomical location and line color indicates the abnormality. Row a) shows the connection with decreased functional connectivity, row b) shows the connections with increased functional connectivity and row c) indicates two connections showing the higher differences between SCA7 and healthy control (p < 0.0001, see Table 1). Note that for side views translucent nodes are located in the opposite hemisphere.