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Table 1 Table of major transporters and receptors involved in this study

From: Functional contributions of glutamate transporters at the parallel fibre to Purkinje neuron synapse–relevance for the progression of cerebellar ataxia

Receptor/Transporter

Location

Antagonist

EAAT1

Bergmann Glia

TBOA

EAAT2

Bergmann Glia

TBOA

EAAT3

Purkinje neuron (PN)

TBOA

EAAT4

Perisynaptic on PN

TBOA

AMPA/Kainate

PN, postsynaptic density (PSD)

CNQX

mGluR1

PN, edge of PSD

(S)-MCPG

mGluR4

Parallel fiber presynapse

MPPG

  1. A list of major transporters and receptors used in this study along with their associated antagonists and locations. DL-TBOA = DL-threo-β-Benzyloxyaspartic acid, CNQX = 6-cyano-7-nitroquinoxaline-2,3-dione, (S)-MCPG = (S)-α-Methyl-4-carboxyphenylglycine, MPPG = (RS)-α-Methyl-4-phosphonophenylglycine.