Figure 3
From: Histaminergic afferent system in the cerebellum: structure and function
Histamine precisely modulates trunk, proximal and distal muscles through the cerebellar fastigial and interpositus nuclei, respectively. (A) Walking track of hindfeet of a normal rat. (B) Microinjection of histamine into the fastigial rather than interpositus nuclei induced a narrower stride width. (C) Microinjection of histamine into the interpositus but not fastigial nuclei induced a longer stride length. (D) Microinjection of histamine into the interpositus but not fastigial nuclei increased the endurance time of suspension. **P < 0.01. SL, stride length; SW, stride width. Modified from He et al., Behav Brain Res., 228:44–52, 2012.