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Table 5 The monthly changes of MRS metabolites in different groups of patients â•¥

From: The merit of proton magnetic resonance spectroscopy in the longitudinal assessment of spinocerebellar ataxias and multiple system atrophy-cerebellar type

 

Cerebellar hemispheres

Vermis

 

NAA/Cr

Cho/Cr

NAA/Cho

NAA/Cr

Cho/Cr

NAA/Cho

p #

0.471

0.168

0.261

0.693

0.269

0.273

SCA2

0.09 ± 0.17

0.13 ± 0.14

−0.08 ± 0.28

−0.25 ± 0.53

−0.18 ± 0.23

−0.08 ± 0.68

SCA3

−0.04 ± 0.22

−0.04 ± 0.26

0.01 ± 0.61

−0.07 ± 0.20

0.05 ± 0.21

−0.22 ± 0.37

SCA6

0.06 ± 0.22

−0.11 ± 0.16

0.27 ± 0.44

−0.18 ± 0.13

−0.16 ± 0.16

0.00 ± 0.45

MSA-C

0.14 ± 0.59

0.02 ± 0.37

0.33 ± 1.14

0.03 ± 0.32

−0.14 ± 0.36

0.51 ± 0.86

  1. SCA2: Spinocerebellar ataxia type 2; SCA3: Spinocerebellar ataxia type 3; SCA6: Spinocerebellar ataxia type 6; MSA-C: Multiple system atrophy- cerebellar type.
  2. â•¥Data are presented as 100X MRS ratios.
  3. #Kruskal-Wallis test.