Fig. 1

Heatmap that represents the variability of cerebellar dysfunction and its characteristic pattern for SCA3. Central heatmap represents the affection of each patient (ordered according the dendrogram of patients, top) in each SARA item (ordered according the dendrogram of SARA items, right). The closer the junction line between two elements is to heatmap in a dendrogram, the more similar they are. Each colour-coded cell represents the value for each SARA item in a particular patient, as shown in the top left scale. The lower cells represent the group of affection, sex and disease duration (years). Note three types of patients according to severity of cerebellar signs. Heatmap shows a fingerprint of cerebellar signs in SCA3: gait and stance are impaired in the majority of patients and, in contrast, other variables, are relatively more preserved in a significant proportion of patients