Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia—a case series

Table 1 Clinical characteristics and ambulatory functions of the patients

Demographic characteristics
N	18 (9 women)
mean age (years)	58.83 ± 12.0
height (m)	1.73 ± 0.07
weight (kg)	72.6 ± 6.1
duration of symptoms (months)	72.0 ± 29.3
median SARA score [range]	12 [8; 20]
Etiology of ataxia
sporadic	10x SAOA, 2x MSA-C
hereditary	2x ADA, 1 x CACNA-1A mutation, 2x SCA 2, 1x SCA 1
Walking performance
median FGA score [range]	19 [6; 30]
Ambulatory status
independent	12
Intermediate use of aides	4
prevalent use of aides	2

Legend: Abbreviations: FGA Functional Gait Assessment [7], SARA Scale for the Assessment and Rating of Ataxia [6], SAOA Sporadic Adult Onset Cerebellar Atrophy, ADA Autosomal Dominant Ataxia, CACNA-1A Calcium Channel. voltage-dependent Alpha 1A subunit (P/Q type), SCA Spino Cerebellar Ataxia MSA-C multiple system atrophy with cerebellar features

ISSN: 2053-8871