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Table 2 Patient characteristics, categorized by patient number, gender, age, etiology, duration of disease, neuro-ophthalmological findings, participation in a previous case study [3] as well a clinical outcome scores before and under treatment with Acetyl-DL-leucine

From: Acetyl-DL-leucine improves gait variability in patients with cerebellar ataxia—a case series

ID Age ataxia type duration neuro-ophthalmological findings SARA pre SARA post Study
gender Strupp et al. 2013 [3]
1 73, m SAOA >24 8 12.5 9.5  
2 57, w ADA >120 1, 3 8.0 6.0 X
3 73, w SAOA 24 1, 2, 4 20.0 15.0  
4 54, w MSA-C 36 1, 2, 5, 8 13.0 12.0  
5 59, m SCA 2 56 1, 2, 7, slow saccades 16.0 12.5  
6 23, m SCA 2 36 1, 2, 7, slow saccades 13.0 9.0 X
7 68, w ADA >120 1, 2, 3, 6, 7, 8, hypometric saccades 17.0 11,0 X
8 60, m SAOA 24 1, 6 14.0 12.5 X
9 68, w MSA-C 36 1, 2 10,0 9.5  
10 54, m SAOA 60 1, 2, 6, 8 12.0 9.5  
11 63, w SAOA >120 1, 2, 3, 4, 6, 7 14.5 12.5 X
12 51, m SAOA 36 1, 2, 3, 6, 7 hypometric saccades 14.0 12.0 X
13 51, w EA 2 24 1 17.0 16.0  
14 49, m SAOA 36 1, 2, 6, 7 16.5 15.5  
15 63, w SAOA >120 1, 2, 3, 4, 6, 7 11.5 7.0 X
16 67, m SAOA 48 1, 2, 4 13.5 11.5  
17 60, m SAOA 36 1, 3, 5, 8 16.0 12.5  
18 47, w SCA 1 36 1, 2, 5 (bilateral), 6, 7, hypermetric saccades 17.0 9.5 X
  1. Legend: Abbrevations: m man, w woman, SCA spino cerebellar ataxia, EA 2 episodic ataxia type 2, MSA-C multiple system atrophy with cerebellar features, SAOA sporadic adult-onset ataxia of unknown etiology, ADA autosomal dominant cerebellar ataxia, 1 saccadic smooth pursuit, 2 gaze-evoked nystagmus, 3 head-shaking nystagmus, 4 rebound nystagmus, 5 pathological head-thrust test (uni- or bilateral), 6 impaired visual fixation suppression of the VOR, 7 pathological optokinetic reflex, 8 downbeat nystagmus