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Fig. 2 | Cerebellum & Ataxias

Fig. 2

From: Cerebellar fastigial nucleus: from anatomic construction to physiological functions

Fig. 2

Major FN efferent pathways and their related somatic motor and nonsomatic functions. Through the descending projections to the brainstem, including the vestibular nuclei and the medullary/pontine reticular formations, and the bi-synapses ascending pathways to the primary motor cortex, FN holds a key position in axial and proximal motor control (red). FN also projects to the rostral interstitial nucleus of the medial longitudinal fasciculus and the paramedian pontine reticular formation in the pontine reticular formation to control ocular movement (blue). In addition, FN sends direct projections to the hypothalamus, visceral-related nuclei/regions in the medullary reticular formations and the limbic system to participate in feeding (purple), cardiovascular (orange), respiratory (brown) and emotional (green) regulations. FN, fastigial nucleus; M1, primary motor cortex; MRF, medullary reticular formation; NA, nucleus acumbens; NGC, gigantocellular nucleus; NTS, nucleus of solitary tract; PPRF, paramedian pontine reticular formation; PRF, pontine reticular formation; PRN, paramedian reticular nucleus; riMLF, rostral interstitial nucleus of the medial longitudinal fasciculus; VL, ventrolateral nucleus of the thalamus

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