Cerebellum & Ataxias

Table 5 Correlation coefficients between ICARS scores and two MRI biomarkers according to the subtypes of cerebellar ataxia

From: MRI-based cerebellar volume measurements correlate with the International Cooperative Ataxia Rating Scale score in patients with spinocerebellar degeneration or multiple system atrophy

				ICARS total score				ICARS domain I
Subtype		n	Cerebellar volume	p value	Midbrain AP diameter	p value	Cerebellar volume	p value	Midbrain AP diameter	p value
SCA	all patients	34	−0.306	0.079	−0.176	0.319	−0.340	0.049	−0.168	0.342
	SCA1	3	----	----	----	----	----	----	----	----
	SCA2	3	----	----	----	----	----	----	----	----
	SCA3	7	−0.068	0.885	−0.279	0.545	−0.094	0.842	−0.395	0.380
	SCA31	2	----	----	----	----	----	----	----	----
	SCA6	13	–0.571*	0.042	−0.251	0.409	–0.580*	0.038	−0.311	0.301
	SCAx	6	–0.943*	0.005	0.029	0.957	–0.943*	0.005	0.371	0.468
CCA	all patients	18	0.155	0.539	0.023	0.928	−0.073	0.772	−0.050	0.843
MSA	all patients	34	–0.593*	0.001	−0.367^*	0.033	–0.598*	0.001	–0.463*	0.006

Values of correlation coefficient are Spearman’s rho
SCA indicates spinocerebellar ataxia, SCAx the type of SCA was unknown, CCA cortical cerebellar atrophy, MSA multiple system atrophy
* p < 0.05

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ISSN: 2053-8871

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