Alcohol-related cerebellar degeneration: not all down to toxicity?

Table 2 Serological characteristics of patients with alcohol ataxia

Patient ID	Gender	Age at study, y	HLA DQ2/DQ8	Antigliadin IgA and/or IgG	Anti-TG6 IgA and/or IgG	PC stained	GL stained
8	M	33	DQ2		IgA		+
9^a	M	41					+
20	M	50	DQ8			+	++
27	M	67					++
28	M	56		IgA		+	+
30^a	M	46					+
31	M	50				++	+
32	M	66			IgA	++	+
33	M	58	DQ8
37	M	53	DQ2	IgA			+
38	F	56		IgA			+
45	M	49	DQ8				+
47	F	60		IgA
49^a	M	51	DQ8	IgA, IgG	IgA
55	F	48	DQ2			+
62	M	41
69	M	58
92	M	64	DQ8			++	+
100	M	55	DQ2		IgA
101	F	49	DQ2				+
103	F	48	DQ8	IgA			+
104	M	55	DQ2				+
107^a	M	46	DQ2	IgA	IgA	++	++
116	M	51	DQ8		IgG		++
119	M	48			IgA		++
120^a	M	50			IgA		+
121	M	45					+
122^a	M	50		IgA	IgA		+
125	F	66	DQ2		IgA
128	M	68	DQ2		IgA
132	M	62
133^a	M	59	DQ2	IgA	IgA	+	++
134	F	58				+
135	M	57		IgA	IgA	+
136^a	M	47		IgA	IgA	+
139	M	65	DQ2	IgA, IgG	IgA, IgG
143	M	67		IgG
145	M	81					+

^asubgroup chronic liver disease and ataxia (CLDA), y years, TG6 transglutaminase 6, PC Purkinje cell layer, GL granular layer, + weak staining, ++ strong staining

ISSN: 2053-8871