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Table 3 18F-FPEB binding potential throughout the brain as revealed by positron emission tomography (PET)

From: Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study

Region

Control

Autism

t-value

P

Amygdala

3.93 ± 0.64

3.69 ± 0.57

0.58

0.58

Caudate nucleus

4.28 ± 0.47

4.56 ± 0.62

0.67

0.52

Cerebellum

1.07 ± 0.10

1.25 ± 0.068

3.17

0.016

Cingulate

4.33 ± 0.43

4.42 ± 0.23

0.42

0.68

Entorhinal area

1.78 ± 0.71

2.75 ± 0.59

2.19

0.065

Frontal lobe

4.11 ± 0.39

4.28 ± 0.22

0.87

0.41

Fusiform gyrus

3.86 ± 0.49

3.69 ± 0.52

0.47

0.65

Globus pallidus

1.12 ± 0.14

1.28 ± 0.15

1.58

0.16

Hippocampus

3.74 ± 0.67

3.66 ± 0.52

0.21

0.84

Insula

4.58 ± 0.62

4.49 ± 0.51

0.22

0.83

Occipital lobe

3.22 ± 0.39

3.35 ± 0.15

0.79

0.46

Paracentral gyrus

2.89 ± 0.44

3.36 ± 0.32

1.83

0.11

Parahippocampus

3.25 ± 0.09

3.55 ± 0.40

1.22

0.26

Parietal lobe

3.93 ± 0.36

4.10 ± 0.14

1.08

0.32

Precentral gyrus

3.55 ± 0.38

3.86 ± 0.12

1.89

0.10

Precuneus

3.87 ± 0.24

4.19 ± 0.20

2.13

0.071

Postcentral gyrus

3.44 ± 0.22

3.82 ± 0.20

2.60

0.036

Putamen

3.90 ± 0.54

4.18 ± 0.33

0.91

0.39

Temporal lobe

4.23 ± 0.57

4.23 ± 0.30

0.02

1.00

Thalamus

2.43 ± 0.28

2.50 ± 0.29

0.37

0.72

Ventral striatum

4.75 ± 0.66

5.10 ± 0.50

0.89

0.40

  1. Italicized values represent significant or near-significant findings