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Table 4 Psychiatric Symptoms Across Neurobehavioral Profile of CCAS

From: Cerebellar cognitive affective syndrome: insights from Joubert syndrome

  Positive Symptoms
  Case 1 Case 2 Case 3
Attentional Control
 Distractibility + + +
 Hyperactivity    
Emotional Control
 Impulsivity    
 Mood Lability +   
 Anxiety, panic symptoms +   
 Incongruous affect +   
Autism Spectrum
 Stereotypical behaviors    
 Self-stimulation behaviors    
Psychosis Spectrum
 Illogical thought processes    +
 Paranoia    +
 Hallucinations    +
Social Skill Set
 Anger, aggression + + +
 Irritability   + +
 Oppositional behaviors    
  Negative Symptoms
  Case 1 Case 2 Case 3
Attentional Control
 Difficulty shifting focus of attention   + +
Emotional Control
 Sadness, depression +   
 Anhedonia    
 Apathy    
Autism Spectrum
 Avoidant behaviors    
 Sensory overload    
Psychosis Spectrum
 Reduced empathy    +
 Muted affect    
 Blunting    
Social Skill Set
 Passivity    
 Difficulty interpreting social cues and pragmatics + + +
  1. + Represents clinical presence of psychiatric symptom based on informant report and qualitative analysis by the examiner of clinical information