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Table 4 Patterns of changes in size in focal abnormal signal intensities (FASI) on brain MRI over time in patients with NF1 are displayed. The number (%) of patients for each pattern and brain location is shown

From: Cerebellar radiological abnormalities in children with neurofibromatosis type 1: part 2 - a neuroimaging natural history study with clinical correlations

aPattern type

Cerebellum (n = 35)

Brainstem (n = 28)

Thalamus/ Hypothalamus (n = 14)

Basal ganglia/ Internal capsule (n = 28)

Cerebral (n = 17)

A

6 (17.1)

10 (35.7)

6 (42.9)

10 (35.7)

4 (23.5)

B

12 (34.3)

9 (32.1)

3 (21.4)

12 (42.9)

7 (41.2)

C

14 (40)

7 (25)

5 (35.7)

4 (14.3)

1 (5.9)

D

3 (8.6)

2 (7.1)

0

2 (7.1)

5 (29.4)

  1. aPattern types:
  2. A: FASI has remained stable in size or has decreased in size before stabilizing again
  3. B: FASI has been increasing in size or a new FASI has developed, which eventually either got smaller, stabilized or disappeared. FASI may have been preceded by a period of stability in size or a decrease in size before the enlargement occurred
  4. C: FASI has been getting smaller in size or has disappeared
  5. D: FASI has been increasing in size or a new FASI has developed. These changes may have been preceded by a period of stability in size or a decrease in size before the enlargement occurred