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Table 4 Patterns of changes in size in focal abnormal signal intensities (FASI) on brain MRI over time in patients with NF1 are displayed. The number (%) of patients for each pattern and brain location is shown

From: Cerebellar radiological abnormalities in children with neurofibromatosis type 1: part 2 - a neuroimaging natural history study with clinical correlations

aPattern type Cerebellum (n = 35) Brainstem (n = 28) Thalamus/ Hypothalamus (n = 14) Basal ganglia/ Internal capsule (n = 28) Cerebral (n = 17)
A 6 (17.1) 10 (35.7) 6 (42.9) 10 (35.7) 4 (23.5)
B 12 (34.3) 9 (32.1) 3 (21.4) 12 (42.9) 7 (41.2)
C 14 (40) 7 (25) 5 (35.7) 4 (14.3) 1 (5.9)
D 3 (8.6) 2 (7.1) 0 2 (7.1) 5 (29.4)
  1. aPattern types:
  2. A: FASI has remained stable in size or has decreased in size before stabilizing again
  3. B: FASI has been increasing in size or a new FASI has developed, which eventually either got smaller, stabilized or disappeared. FASI may have been preceded by a period of stability in size or a decrease in size before the enlargement occurred
  4. C: FASI has been getting smaller in size or has disappeared
  5. D: FASI has been increasing in size or a new FASI has developed. These changes may have been preceded by a period of stability in size or a decrease in size before the enlargement occurred