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Table 6 The number (No.) of patients with a) optic pathways gliomas, b) mass effect from focal abnormal signal intensities (FASI), and c) contrast enhancement of FASI on their first and subsequent MRI scans is shown

From: Cerebellar radiological abnormalities in children with neurofibromatosis type 1: part 2 - a neuroimaging natural history study with clinical correlations

MRI number No. of patients Median age at MRI (min.-max.) in years aNo. of patients with optic pathways gliomas The no. of patients with FASI displaying:
aMass effect bContrast enhancement
First 50 7.3 (1.2–18.2) 18 3 5
Second 36 9.4 (1.8–23.4) 17 2 3
Third 28 11 (2.8–24.4) 16 2 4
Fourth 21 10.1 (3.3–25.4) 16 2 4
Fifth 16 10.6 (4.4–26.4) 11 1 2
Sixth 15 11.2 (5.4–27.5) 11 0 4
Seventh 12 10.2 (5.8–27.6) 10 0 3
Eighth 10 12.5 (7.4–27.7) 9 0 4
Ninth 10 13.7 (8.1–28.1) 9 0 4
Tenth 8 15.9 (9.2–28.3) 7 0 4
Eleventh 7 16.9 (13–28.6) 6 0 3
Twelfth 5 17.7 (15–28.8) 4 1 3
Thirteenth 3 17.8 (16.1–21.4) 2 0 2
Fourteenth 2 20.4 (18.9–21.9) 1 0 1
Fifteenth 2 21.1 (19.1–23) 1 0 1
Sixteenth 1 19.9 1 0 1
  1. aIn one patient the information could not be obtained since relevant images were degraded by motion artifacts
  2. bIn 6 patients, no contrast was given in one of their scans (further details and discussion on these patients can be found in part 1 of this investigation), min.: minimum, max.: maximum