Fig. 2

An axial brain MRI of a 22 months old female with NF1 is shown. There are bilateral extensive confluent areas of FLAIR signal abnormalities with increased signal intensity involving the internal capsule bilaterally, basal ganglia, thalami, hypothalamus, and cerebral peduncles. There is mass effect on the posterior horns of the lateral ventricles and on the third ventricle causing dilatation of the posterior horns