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Table 4 Summary of imaging results across the 2 groups of ataxic patients (MSA-C, SAOA) and healthy control subjects. One-way ANOVA did not demonstrate a significant difference in Cho/Cr from the hemisphere, so post hoc testing was not preformed

From: Is 1H-MR spectroscopy useful as a diagnostic aid in MSA-C?

  MSA-C SAOA MSA-C vs SAOA Controls MSA-C compared to controls
Mean SD Mean SD P-value Mean SD P-value
Vermis NAA/Cr 0.67 0.12 0.82 .16 P = 0.003‡ 0.99 0.10 P < 0.001+‡
Vermis Cho/Cr 0.62 0.25 0.76 .18 P > 0.05 0.80 0.08 P = 0.040+
Hemisphere NAA/Cr 0.72 0.25 0.97 .20 P = 0.001‡ 1.01 0.09 P < 0.001+‡
Hemisphere Cho/Cr 0.70 0.21 0.82 .22 P > 0.05 0.78 0.12 P > 0.05
Brainstem volume (% of TICV) 0.72 0.22 1.16 .18 P < 0.001‡ 1.25 0.19 P < 0.001+‡
Cerebellum volume (% of TICV) 5.64 0.60 4.97 1.12 P > 0.05 7.53 1.15 P < 0.001+‡
Brainstem volume (cm3) 10.86 3.33 17.02 2.49 P < 0.001+‡ 18.95 2.64 P < 0.001+‡
Cerebellum volume (cm3) 82.17 8.16 72.87 16.29 P = 0.078+ 115.28 15.14 P < 0.001
  1. +ANOVA with Tukey’s HSD post hoc
  2. ‡remain statistically significant after Bonferoni correction