Fig. 1
From: Should we investigate mitochondrial disorders in progressive adult-onset undetermined ataxias?
(a) Axial T2-weighted, (b) axial FLAIR and (c) sagittal T2-weighted brain MR imaging showing global cerebellar atrophy (white arrows) with normal brainstem volume. Muscle biopsy disclosed increased subsarcolemmal mitochondrial proliferation with typical ragged-red fibers (RRF) in modified Gömöri Trichrome stain (d; white arrows) and ragged-blue fibers in modified succinate-dehydrogenase (SDH) reaction (E; black arrows)