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Table 1 summary of the immunofluorescence findings per group of patients with immune, genetic or degenerative ataxias

From: Indirect immunofluorescent assay as an aid in the diagnosis of suspected immune mediated ataxias

  Immune mediated cerebellar ataxias (190 patients) Control groups of ataxias (110 patients)
Number of patients positive on immunofluorescence (percentage positive) 172/190 (91%) 5/110 (5%)
Ataxia subgroups (number of patients) Gluten Ataxia (143) Primary Autoimmune Carebellar Ataxias (32) Anti-GAD Ataxia (15) Genetically Confirmed Ataxias (60) Cerebellar variant of Multi-System Atrophy (50)
Number of patients with positive immunofluorescence per group (percentage positive) 126/143 (88%) 32/32 (100%) 14/15 (93%) 3/60 (5%) 2/40 (4%)
Type of staining per group (percentage from positive patients) Hu like 109/126 (87%)
Yo like 7/126 (6%)
CV2 like 4/126 (3%)
amphiphysin like 3/126 (2%)
Tr like 2/126 (2%)
Ma2 like 1/126 (1%)
Hu like 26/32 (81%)
Yo like 4/32 (13%)
(one had both Hu and Yo like staining)
amphiphysin like 2/32 (6%)
CV2 like 1/32 (3%)
Hu like 10/14 (71%)
amphiphysin like 4/14 (29%)
Hu like 2/3 (66%)
Yo like 1/3 (33%)
Hu like 1/2 (50%) amphiphysin like 1/2 (50%)