Table 1 summary of the immunofluorescence findings per group of patients with immune, genetic or degenerative ataxias
From: Indirect immunofluorescent assay as an aid in the diagnosis of suspected immune mediated ataxias
Immune mediated cerebellar ataxias (190 patients) | Control groups of ataxias (110 patients) | ||||
|---|---|---|---|---|---|
Number of patients positive on immunofluorescence (percentage positive) | 172/190 (91%) | 5/110 (5%) | |||
Ataxia subgroups (number of patients) | Gluten Ataxia (143) | Primary Autoimmune Carebellar Ataxias (32) | Anti-GAD Ataxia (15) | Genetically Confirmed Ataxias (60) | Cerebellar variant of Multi-System Atrophy (50) |
Number of patients with positive immunofluorescence per group (percentage positive) | 126/143 (88%) | 32/32 (100%) | 14/15 (93%) | 3/60 (5%) | 2/40 (4%) |
Type of staining per group (percentage from positive patients) | Hu like 109/126 (87%) Yo like 7/126 (6%) CV2 like 4/126 (3%) amphiphysin like 3/126 (2%) Tr like 2/126 (2%) Ma2 like 1/126 (1%) | Hu like 26/32 (81%) Yo like 4/32 (13%) (one had both Hu and Yo like staining) amphiphysin like 2/32 (6%) CV2 like 1/32 (3%) | Hu like 10/14 (71%) amphiphysin like 4/14 (29%) | Hu like 2/3 (66%) Yo like 1/3 (33%) | Hu like 1/2 (50%) amphiphysin like 1/2 (50%) |