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Fig. 1 | Cerebellum & Ataxias

Fig. 1

From: Midbrain atrophy related to parkinsonism in a non-coding repeat expansion disorder: five cases of spinocerebellar ataxia type 31 with nigrostriatal dopaminergic dysfunction

Fig. 1

Schematic diagram of the study design. Number of patients included in the cross-sectional (□) and longitudinal (■) imaging analyses. All five patients with NSDD(+) were male. Therefore, for statistical comparison, the patients with NSDD(−), PD, and PSP were further divided into male patients with NSDD(−) (NSDD(−)m), male patients with PD (PDm), and male patients with PSP (PSPm). Serial MRI scans were done for all five patients with NSDD(+) and nine of 14 patients with NSDD(−), accounting for the difference in the number of patients with NSDD(−) between the cross-sectional and longitudinal analyses. NSDD, nigrostriatal dopaminergic dysfunction; NSDD(+), SCA31 with NSDD; NSDD(−), SCA31 without NSDD; PD, Parkinson’s disease; PSP, progressive supranuclear palsy; SCA31, spinocerebellar ataxia type 31

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