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Fig. 2 | Cerebellum & Ataxias

Fig. 2

From: Midbrain atrophy related to parkinsonism in a non-coding repeat expansion disorder: five cases of spinocerebellar ataxia type 31 with nigrostriatal dopaminergic dysfunction

Fig. 2

Midbrain atrophy in a representative case of NSDD and the results of M/P area ratio. Midsagittal T1-weighted MRI of a representative case from the NSDD(+) (a), NSDD(−) (b), PD (c), and PSP (d). e Cross-sectional imaging analysis of the M/P area ratio showing a clear difference between the NSDD(+) and NSDD(−) groups (p = 0.005), and between the NSDD(+) and PD groups (p = 0.001). In line with previous studies, the M/P area ratio showed a clear difference between the PD and PSP groups (p < 0.001). *Significant difference (p < 0.05). M/P, midbrain-to-pons; NSDD, nigrostriatal dopaminergic dysfunction; NSDD(+), SCA31 with NSDD; NSDD(−), SCA31 without NSDD; PD, Parkinson’s disease; PSP, progressive supranuclear palsy; SCA31, spinocerebellar ataxia type 31

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Cerebellum & Ataxias

ISSN: 2053-8871