| NSDD(+) | NSDD(−) | NSDD(−)m | PD | PDm | PSP | PSPm |
---|---|---|---|---|---|---|---|
Number | 5 | 14 | 8 | 32 | 17 | 15 | 8 |
M: F ratio | 5: 0 | 8: 6 | 8: 0 | 17: 15 | 17: 0 | 8: 7 | 8: 0 |
Age at disease onset | 63.6 ± 8.2 (52–73) | 57.6 ± 7.8 (40–70) p = 0.191 | 54.6 ± 8.0 (40–65) p = 0.101 | 66.0 ± 6.2 (53–79) p = 0.462 | 67.0 ± 5.2 (55–75) p = 0.302 | 72.1 ± 8.2 (60–87) p = 0.074 | 67.9 ± 7.5 (60–85) p = 0.396 |
Age at MRI | 74.0 ± 11.3 (61–85) | 68.4 ± 13.5 (44–87) p = 0.415 | 65.3 ± 14.9 (44–87) p = 0.285 | 74.4 ± 6.0 (61–83) p = 0.936 | 75.7 ± 5.3 (66–83) p = 0.758 | 76.7 ± 7.7 (62–89) p = 0.546 | 72.8 ± 7.8 (62–88) p = 0.817 |
Disease duration at MRI (year) | 10.4 ± 6.8 (4–21) | 10.7 ± 8.2 (2–30) p = 0.889 | 10.6 ± 9.5 (2–30) p = 0.711 | 8.4 ± 3.8 (3–18) p = 0.562 | 8.7 ± 3.5 (3–17) p = 0.664 | 4.7 ± 3.1 (1–11) p = 0.028a | 4.9 ± 3.3 (1–10) p = 0.047a |
Midbrain area (mm2) | 88.8 ± 15.2 (71.9–105.2) | 122.2 ± 24.7 (82.7–172.6) p = 0.012a | 122.0 ± 30.6 (82.7–172.6) p = 0.048a | 113.3 ± 17.1 (72.1–147.3) p = 0.005a | 114.1 ± 15.6 (88.7–141.7) p = 0.005a | 67.6 ± 14.8 (40.9–96.3) p = 0.013a | 62.8 ± 10.9 (40.9–73.8) p = 0.004a |
Pons area (mm2) | 512.5 ± 46.0 (455.2–566.9) | 500.9 ± 43.8 (408.0–572.9) p = 0.620 | 514.7 ± 41.8 (459.8–572.9) p = 0.931 | 508.5 ± 63.1 (370.5–676.4) p = 0.890 | 535.6 ± 66.7 (418.0–676.4) p = 0.481 | 446.2 ± 46.8 (354.3–510.4) p = 0.013a | 458.0 ± 41.6 (381.7–510.4) p = 0.049a |
Cerebellum area (mm2) | 622.7 ± 96.8 (501.8–732.0) | 628.8 ± 102.2 (449.0–812.8) p = 0.909 | 649.9 ± 92.6 (510.3–812.8) p = 0.623 |  |  |  |  |
M/P area ratio | 0.173 ± 0.023 (0.148–0.202) | 0.244 ± 0.047 (0.180–0.333) p = 0.005a | 0.235 ± 0.049 (0.180–0.333) p = 0.022a | 0.224 ± 0.031 (0.146–0.296) p = 0.001a | 0.215 ± 0.027 (0.146–0.251) p = 0.006a | 0.151 ± 0.026 (0.107–0.210) p = 0.111 | 0.137 ± 0.017 (0.107–0.157) p = 0.007a |
C/P area ratio | 1.214 ± 0.142 (1.034–1.395) | 1.255 ± 0.176 (0.927–1.591) p = 0.639 | 1.278 ± 0.174 (1.119–1.613) p = 0.502 |  |  |  |  |