Table 1 Classification of immune-mediated cerebellar ataxias (IMCAs)

1. Autoimmunity targeting mainly the cerebellum^a or related structures^b:

 Cerebellar autoimmunity triggered by another disease or condition:

  Gluten ataxia (gluten sensitivity)

  Acute cerebellitis (infection)

  Miller Fisher syndrome (infection)

  Paraneoplastic cerebellar degenerations (neoplasm)

 Cerebellar autoimmunity not triggered by another disease or condition:

  Anti-GAD65 Ab-associated cerebellar ataxias ^c

  Steroid-responsive IMCAs with anti-thyroid antibodies

  Primary autoimmune cerebellar ataxia (PACA)

  Others

2. Autoimmunity that targets various parts of the CNS simultaneously:

 Multiple sclerosis

 Ataxia in the context of connective tissue diseases such as systemic lupus erythematosus