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Cerebellum & Ataxias

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  1. Content type: Review

    The cerebellum is a vulnerable target of autoimmunity in the CNS. The category of immune-mediated cerebellar ataxias (IMCAs) was recently established, and includes in particular paraneoplastic cerebellar degen...

    Authors: Hiroshi Mitoma, Mario Manto and Christiane S. Hampe

    Citation: Cerebellum & Ataxias 2017 4:16

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  2. Content type: Research

    The control of grip forces when moving a hand held object is impaired in patients with cerebellar degeneration. We asked the question whether after-effects of anodal transcranial direct current stimulation (tD...

    Authors: Liane John, Michael Küper, Thomas Hulst, Dagmar Timmann and Joachim Hermsdörfer

    Citation: Cerebellum & Ataxias 2017 4:15

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  3. Content type: Case report

    Hemicerebellitisis a rare acquired condition, typical of the pediatric age. A residual switched handedness may develop after remission of acute cerebellar symptoms.

    Authors: Mario Mascalchi, Matteo Lenge, Andrea Bianchi, Emanuele Bartolini, Gioele Gavazzi, Flavio Giordano and Renzo Guerrini

    Citation: Cerebellum & Ataxias 2017 4:14

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  4. Content type: Research

    Damage to the cerebellum may lead to motor dysfunctions, but also to the neuropsychological deficits that comprise the Cerebellar Cognitive Affective Syndrome (CCAS). It can affect executive functions, attenti...

    Authors: Eva Bolceková, Matej Mojzeš, Quang Van Tran, Jaromír Kukal, Svatopluk Ostrý, Petr Kulišťák and Robert Rusina

    Citation: Cerebellum & Ataxias 2017 4:13

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  5. Content type: Research

    Multiple system atrophy (MSA) is a rare progressive neurodegenerative disorder for which brief yet sensitive scale is required in order for use in clinical trials and general screening. We previously compared ...

    Authors: Masaaki Matsushima, Ichiro Yabe, Ikuko Takahashi, Makoto Hirotani, Takahiro Kano, Kazuhiro Horiuchi, Hideki Houzen and Hidenao Sasaki

    Citation: Cerebellum & Ataxias 2017 4:11

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  6. Content type: Research

    The pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cereb...

    Authors: Jonathan P. Dyke, Eric Cameron, Nora Hernandez, Ulrike Dydak and Elan D. Louis

    Citation: Cerebellum & Ataxias 2017 4:10

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  7. Content type: Research

    The rate of disease progression differs among patients with degenerative cerebellar ataxia. The uncertain natural course in individual patients hinders clinical trials of promising treatments. In this study, w...

    Authors: Rie Sasaki, Futaba Maki, Daisuke Hara, Shigeaki Tanaka and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2017 4:9

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  8. Content type: Case report

    Granule cell neuronopathy (GCN) is a rare disease caused by the JC virus, leading to degeneration of cerebellar granule cell neurons. Primarily described in patients with AIDS, it has also been diagnosed in pa...

    Authors: Kathryn B. Holroyd, Elias S. Sotirchos, Scott R. DeBoer, Kelly A. Mills and Scott D. Newsome

    Citation: Cerebellum & Ataxias 2017 4:8

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  9. Content type: Research

    Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant inherited neurodegenerative disorder. Several post-mortem and imaging studies have shown cerebellar and brainstem atroph...

    Authors: Carlos R. Hernandez-Castillo, Rosalinda Diaz, Aurelio Campos-Romo and Juan Fernandez-Ruiz

    Citation: Cerebellum & Ataxias 2017 4:7

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  10. Content type: Review

    Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas...

    Authors: Matteo Bologna and Alfredo Berardelli

    Citation: Cerebellum & Ataxias 2017 4:6

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  11. Content type: Case report

    Progressive multifocal leukoencephalopathy (PML) is a demyelinating disorder of the central nervous system caused by reactivation of the JC-virus and is in most cases associated with underlying immunosuppressi...

    Authors: Ivan Kmezic, Jan Weinberg, Dan Hauzenberger, Farouk Hashim, Evangelia Kollia, Monika Klimkowska, Inger Nennesmo and Martin Paucar

    Citation: Cerebellum & Ataxias 2017 4:5

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  12. Content type: Review

    Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9. Due to epigenetic alteratio...

    Authors: Katrin Bürk

    Citation: Cerebellum & Ataxias 2017 4:4

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  13. Content type: Case report

    Cerebellar mutism syndrome (CMS) or posterior fossa syndrome (PFS) consists of a constellation of neuropsychiatric, neuropsychological and neurogenic speech and language deficits. It is most commonly observed ...

    Authors: E. De Witte, I. Wilssens, D. De Surgeloose, G. Dua, M. Moens, J. Verhoeven, M. Manto and P. Mariën

    Citation: Cerebellum & Ataxias 2017 4:2

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  14. Content type: Case report

    Cerebellar ataxia with sensory ganglionopathy is a rare neurological combination that can occur in some hereditary ataxias including mitochondrial diseases and in gluten sensitivity. Individually each conditio...

    Authors: Panagiotis Zis, Dasappaiah Ganesh Rao, Bart E Wagner, Lucinda Nicholson-Goult, Nigel Hoggard and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2017 4:1

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  15. Content type: Research

    Alcohol-related cerebellar degeneration is one of the commonest acquired forms of cerebellar ataxia. The exact pathogenic mechanisms by which alcohol leads to cerebellar damage remain unknown. Possible autorea...

    Authors: Priya D. Shanmugarajah, Nigel Hoggard, Stuart Currie, Daniel P. Aeschlimann, Pascale C. Aeschlimann, Dermot C. Gleeson, Mohammed Karajeh, Nicola Woodroofe, Richard A. Grünewald and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2016 3:17

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  16. Content type: Review

    Several studies have highlighted the therapeutic potential of transcranial direct current stimulation (tDCS) in patients with neurological diseases, including dementia, epilepsy, post-stroke dysfunctions, move...

    Authors: Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero and Alberto Priori

    Citation: Cerebellum & Ataxias 2016 3:16

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  17. Content type: Research

    Low-frequency electrical stimulation to the motor cortex (LFSMC) depresses the excitability of motor circuits by long-term depression (LTD)-like effects. The interactions between LFSMC and cathodal direct curr...

    Authors: Nordeyn Oulad Ben Taib and Mario Manto

    Citation: Cerebellum & Ataxias 2016 3:15

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  18. Content type: Research

    Progression of clinical symptoms and cerebellar atrophy may vary among subtypes of spinocerebellar degeneration and multiple system atrophy. The aim of this cross-sectional study was to demonstrate the relatio...

    Authors: Daisuke Hara, Futaba Maki, Shigeaki Tanaka, Rie Sasaki and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2016 3:14

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  19. Content type: Research

    There exists a lack of consensus regarding how cerebellar over-activity might influence tremor in Parkinson’s disease (PD). Specifically, it is unclear whether resting or postural tremor are differentially aff...

    Authors: Shannon C. Lefaivre, Matt J. N. Brown and Quincy J. Almeida

    Citation: Cerebellum & Ataxias 2016 3:13

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