From: Immune-mediated cerebellar ataxias: from bench to bedside
Gluten ataxia |
Induction and maintenance therapies: strict gluten-free diet |
Immunosuppressants or IVIg for patients who show no improvement or are negative for gluten-related antibodies |
Paraneoplastic cerebellar degeneration |
Early removal of neoplasm is the first objective of treatment, followed by induction therapy (mPSL, IVIg, immunosuppressants, or/and plasma exchange). Discussion according to associated Abs. Long-term oral PSL, IVIg, immunosuppressants for maintenance therapy |
Anti-GAD65 Ab-associated cerebellar ataxia |
Induction therapy: mPSL, IVIg, immunosuppressants, plasma exchange, or/and rituximab |
Maintenance therapy: continuous oral PSL, IVIg, immunosuppressants, or/and rituximab |