Table 1 Main demographical, clinical and molecular characteristics of the enrolled subjects
Variable | SCA2 patients (N = 48) | Preclinical carriers (N = 25) | Healthy controls (N = 24) |
|---|---|---|---|
Gender (female/male) | 19/29 | 16/9 | 15/9 |
Age (years) | 41.35 ± 9.79 (18–69) | 36.88 ± 9.14 (24–61) | 41.13 ± 11.05 (20–63) |
Age at onset (years) | 30.06 ± 9.06 (9–60) | NA | NA |
Disease duration (years) | 11.71 ± 6.08 (3–29) | NA | NA |
SARA score | 15.81 ± 5.59 (6–30) | 0.76 ± 0.66 (0–2) | 0 |
Unexpanded CAG repeat (units) | 22.08 ± 0.92) (19–27) | 22.84 ± 1.93 (22–29) | 22.54 ± 1.76 (20–30) |
Expanded CAG repeat (units) | 39.81 ± 2.92 (35–47) | 35.76 ± 1.90 (32–39) | NA |