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  1. Content type: Research

    Alcohol-related cerebellar degeneration is one of the commonest acquired forms of cerebellar ataxia. The exact pathogenic mechanisms by which alcohol leads to cerebellar damage remain unknown. Possible autorea...

    Authors: Priya D. Shanmugarajah, Nigel Hoggard, Stuart Currie, Daniel P. Aeschlimann, Pascale C. Aeschlimann, Dermot C. Gleeson, Mohammed Karajeh, Nicola Woodroofe, Richard A. Grünewald and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2016 3:17

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  2. Content type: Review

    Several studies have highlighted the therapeutic potential of transcranial direct current stimulation (tDCS) in patients with neurological diseases, including dementia, epilepsy, post-stroke dysfunctions, move...

    Authors: Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero and Alberto Priori

    Citation: Cerebellum & Ataxias 2016 3:16

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  3. Content type: Research

    Low-frequency electrical stimulation to the motor cortex (LFSMC) depresses the excitability of motor circuits by long-term depression (LTD)-like effects. The interactions between LFSMC and cathodal direct curr...

    Authors: Nordeyn Oulad Ben Taib and Mario Manto

    Citation: Cerebellum & Ataxias 2016 3:15

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  4. Content type: Research

    Progression of clinical symptoms and cerebellar atrophy may vary among subtypes of spinocerebellar degeneration and multiple system atrophy. The aim of this cross-sectional study was to demonstrate the relatio...

    Authors: Daisuke Hara, Futaba Maki, Shigeaki Tanaka, Rie Sasaki and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2016 3:14

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  5. Content type: Research

    There exists a lack of consensus regarding how cerebellar over-activity might influence tremor in Parkinson’s disease (PD). Specifically, it is unclear whether resting or postural tremor are differentially aff...

    Authors: Shannon C. Lefaivre, Matt J. N. Brown and Quincy J. Almeida

    Citation: Cerebellum & Ataxias 2016 3:13

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  6. Content type: Letter to the Editor

    Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-D...

    Authors: Roman Schniepp, Michael Strupp, Max Wuehr, Klaus Jahn, Marianne Dieterich, Thomas Brandt and Katharina Feil

    Citation: Cerebellum & Ataxias 2016 3:8

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  7. Content type: Research

    Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disorder that affects the cerebellar system and other subcortical regions of the brain. As for other cerebellar diseases, the severity of this type o...

    Authors: Irene Pulido-Valdeolivas, David Gómez-Andrés, Irene Sanz-Gallego, Estrella Rausell and Javier Arpa

    Citation: Cerebellum & Ataxias 2016 3:4

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  8. Content type: Case report

    Benign hereditary chorea is a rare disorder which is characterized by early onset, non-progressive choreic movement disturbance, with other hyperkinetic movements and unsteadiness also commonly seen. Hypothyro...

    Authors: Jeanette Koht, Sven Olav Løstegaard, Iselin Wedding, Marie Vidailhet, Malek Louha and Chantal ME Tallaksen

    Citation: Cerebellum & Ataxias 2016 3:3

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  9. Content type: Research

    Spinocerebellar ataxias (SСAs) are a highly heterogeneous group of inherited neurological disorders. The symptoms of ataxia vary in individual patients and even within the same SCA subtype. A study of a four-g...

    Authors: M. I. Shadrina, M. V. Shulskaya, S. A. Klyushnikov, T. Nikopensius, M. Nelis, P. A. Kivistik, A. A. Komar, S. A. Limborska, S. N. Illarioshkin and P. A. Slominsky

    Citation: Cerebellum & Ataxias 2016 3:2

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  10. Content type: Review

    Cerebellar abnormalities are encountered in a high number of neurological diseases that present in the neonatal period. These disorders can be categorized broadly as inherited (e.g. malformations, inborn error...

    Authors: Jessica L. Klein, Monica E. Lemmon, Frances J. Northington, Eugen Boltshauser, Thierry A. G. M. Huisman and Andrea Poretti

    Citation: Cerebellum & Ataxias 2016 3:1

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  11. Content type: Research

    Spinocerebellar ataxia type 28 (SCA28) is related to mutations of the ATPase family gene 3-like 2 gene (AFG3L2). To date, 13 private missense mutations have been identified in families of French, Italian, and Ger...

    Authors: Christine Zühlke, Barbara Mikat, Dagmar Timmann, Dagmar Wieczorek, Gabriele Gillessen-Kaesbach and Katrin Bürk

    Citation: Cerebellum & Ataxias 2015 2:19

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  12. Content type: Case report

    In the majority of right-handed subjects, language processing is subserved by a close interplay between the left cerebral hemisphere and right cerebellum. Within this network, the dominant fronto-insular regio...

    Authors: Kim van Dun, Elke De Witte, Wendy Van Daele, Wim Van Hecke, Mario Manto and Peter Mariën

    Citation: Cerebellum & Ataxias 2015 2:18

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  13. Content type: Research

    Mitochondrial disease can manifest as multi-organ disorder, often with neurological dysfunction. Cerebellar ataxia in isolation or in combination with other features can result from mitochondrial disease yet g...

    Authors: David Bargiela, Priya Shanmugarajah, Christine Lo, Emma L. Blakely, Robert W. Taylor, Rita Horvath, Stephen Wharton, Patrick F. Chinnery and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:16

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  14. Content type: Case Report

    Crossed cerebello-cerebral diaschisis (CCCD) conventionally refers to decreased resting cerebral activity caused by injury to the contralateral cerebellum. We investigated whether functional activation of a co...

    Authors: Takayuki Nakahachi, Ryouhei Ishii, Leonides Canuet and Masao Iwase

    Citation: Cerebellum & Ataxias 2015 2:15

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  15. Content type: Review

    Immune-mediated cerebellar ataxias include gluten ataxia, paraneoplastic cerebellar degeneration, GAD antibody associated cerebellar ataxia, and Hashimoto’s encephalopathy. Despite the identification of an inc...

    Authors: Hiroshi Mitoma, Marios Hadjivassiliou and Jérôme Honnorat

    Citation: Cerebellum & Ataxias 2015 2:14

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  16. Content type: Review

    Following in the vein of studies that concluded that music training resulted in plastic changes in Einstein’s cerebral cortex, controlled research has shown that music training (1) enhances central executive a...

    Authors: Larry Vandervert

    Citation: Cerebellum & Ataxias 2015 2:11

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  17. Content type: Commentary

    Until the end of 18th century, the role of the cerebellum remained obscure. The turning point occurred when Luigi Galvani showed that muscle contraction is due to electricity and Alessandro Volta produced the ...

    Authors: Marinella Coco and Vincenzo Perciavalle

    Citation: Cerebellum & Ataxias 2015 2:10

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  18. Content type: Research

    The aim of this study was to investigate the usefulness of a triaxial accelerometer for the clinical assessment of standing and gait impairment in ataxic patients quantitatively. Fifty-one patients with spinoc...

    Authors: Akira Matsushima, Kunihiro Yoshida, Hirokazu Genno, Asuka Murata, Setsuko Matsuzawa, Katsuya Nakamura, Akinori Nakamura and Shu-ichi Ikeda

    Citation: Cerebellum & Ataxias 2015 2:9

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  19. Content type: Review

    The cerebellum is important for motor control, cognition, and language processing. Afferent and efferent fibers are major components of cerebellar circuitry and impairment of these circuits causes severe cereb...

    Authors: Maryam Rahimi-Balaei, Pegah Afsharinezhad, Karen Bailey, Matthew Buchok, Behzad Yeganeh and Hassan Marzban

    Citation: Cerebellum & Ataxias 2015 2:7

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  20. Content type: Research

    The cerebellum plays an important role for balance control and the coordination of voluntary movements. Beyond that there is growing evidence that the cerebellum is also involved in cognitive functions. How at...

    Authors: Heike Jacobi, Juliane Alfes, Martina Minnerop, Jürgen Konczak, Thomas Klockgether and Dagmar Timmann

    Citation: Cerebellum & Ataxias 2015 2:6

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  21. Content type: Case report

    We report a mother and daughter with autosomal recessive ataxia with occulomotor apraxia in whom sequence analysis of senataxin revealed a dignosis of AOA2 (ataxia with occulomotor apraxia type 2) in both indi...

    Authors: Laurence Newrick, Malcolm Taylor and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:5

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  22. Content type: Commentary

    A 50-year-old man presented with a brief history of slurred speech, unsteadiness, double vision and paraesthesia. He had been unwell for 12 days with campylobacter gastroenteritis. On examination, there was op...

    Authors: Robert D Sandler, Nigel Hoggard and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:3

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  23. Content type: Research

    Spinocerebellar Ataxia Type 3/Machado-Joseph Disease (SCA3/MJD) is a hereditary neurodegenerative disorder resulting from the expansion of CAG repeats in the ATXN3 gene. It is the most common autosomal dominant a...

    Authors: Yanetza González-Zaldívar, Yaimeé Vázquez-Mojena, José M Laffita-Mesa, Luis E Almaguer-Mederos, Roberto Rodríguez-Labrada, Gilberto Sánchez-Cruz, Raúl Aguilera-Rodríguez, Tania Cruz-Mariño, Nalia Canales-Ochoa, Patrick MacLeod and Luis Velázquez-Pérez

    Citation: Cerebellum & Ataxias 2015 2:1

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  24. Content type: Research

    Most adult-onset sporadic ataxias are unexplained, and the claim that many of these may be a result of gluten sensitivity has led to uncertainty as to whether to test for anti-gliadin antibodies (αGAb) and, if...

    Authors: Volga Tarlac, Louise Kelly, Robert P Anderson, Nicole Bye and Elsdon Storey

    Citation: Cerebellum & Ataxias 2014 1:18

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  25. Content type: Research

    Spinocerebellar ataxia (SCA) and multiple system atrophy-cerebellar type (MSA-C) often present with similar clinical manifestations in the beginning. Magnetic resonance spectroscopy (MRS) has been proved to be...

    Authors: Hung-Chieh Chen, Jiing-Feng Lirng, Bing-Wen Soong, Wan Yuo Guo, Hsiu-Mei Wu, Clayton Chi-Chang Chen and Cheng-Yen Chang

    Citation: Cerebellum & Ataxias 2014 1:17

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  26. Content type: Research

    In healthy humans, somatosensory stimulation in the form of 2 h-repetitive peripheral afferent nerve stimulation (SS) increases excitability of the contralateral motor cortex. In this preliminary study, we exp...

    Authors: Suzete Nascimento Farias da Guarda and Adriana Bastos Conforto

    Citation: Cerebellum & Ataxias 2014 1:16

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    The Erratum to this article has been published in Cerebellum & Ataxias 2016 3:11

  27. Content type: Case report

    Opsoclonus-myoclonus syndrome (OMS) is well known as a paraneoplastic syndrome or as a parainfectious neurologic complication. However, OMS associated with a neurodegenerative disorder has not been described p...

    Authors: Kazumasa Shindo, Akiko Onohara, Takanori Hata, Fumikazu Kobayashi, Kaori Nagasaka, Takamura Nagasaka and Yoshihisa Takiyama

    Citation: Cerebellum & Ataxias 2014 1:15

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  28. Content type: Review

    Multiple system atrophy is a rare and fatal neurodegenerative disorder characterized by progressive autonomic failure, ataxia and parkinsonism in any combination. The clinical manifestations reflect central au...

    Authors: Ludovico Ciolli, Florian Krismer, Ferdinando Nicoletti and Gregor K Wenning

    Citation: Cerebellum & Ataxias 2014 1:14

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  29. Content type: Research

    The objective of this clinical open-label trial was to test the safety, tolerability and efficacy of IGF-1 therapy for autosomal dominant cerebellar ataxia (ADCA) patients.

    Authors: Irene Sanz-Gallego, Francisco J Rodriguez-de-Rivera, Irene Pulido, Ignacio Torres-Aleman and Javier Arpa

    Citation: Cerebellum & Ataxias 2014 1:13

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  30. Content type: Review

    Clinical case descriptions and experimental evidence dating back to the early part of the 19th century from time to time documented a range of nonmotor cognitive and affective impairments following cerebellar ...

    Authors: Peter Mariën and Alan Beaton

    Citation: Cerebellum & Ataxias 2014 1:12

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  31. Content type: Research

    Cortical myoclonus with ataxia has only rarely been reported in association with Coeliac Disease (CD). Such reports also suggested that it is unresponsive to gluten-free diet. We present detailed electro-clini...

    Authors: Ptolemaios G Sarrigiannis, Nigel Hoggard, Daniel Aeschlimann, David S Sanders, Richard A Grünewald, Zoe C Unwin and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2014 1:11

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  32. Content type: Case report

    We report the case of a 25 year-old patient who underwent morphological and functional brain magnetic resonance imaging (fMRI) to investigate a left neocerebellar hypoplasia discovered incidentally. We compare...

    Authors: Christophe Habas and Mario Manto

    Citation: Cerebellum & Ataxias 2014 1:6

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