Skip to main content

Articles

Page 2 of 3

  1. Multiple system atrophy (MSA) is a rare progressive neurodegenerative disorder for which brief yet sensitive scale is required in order for use in clinical trials and general screening. We previously compared ...

    Authors: Masaaki Matsushima, Ichiro Yabe, Ikuko Takahashi, Makoto Hirotani, Takahiro Kano, Kazuhiro Horiuchi, Hideki Houzen and Hidenao Sasaki

    Citation: Cerebellum & Ataxias 2017 4:11

    Content type: Research

    Published on:

  2. The pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cereb...

    Authors: Jonathan P. Dyke, Eric Cameron, Nora Hernandez, Ulrike Dydak and Elan D. Louis

    Citation: Cerebellum & Ataxias 2017 4:10

    Content type: Research

    Published on:

  3. The rate of disease progression differs among patients with degenerative cerebellar ataxia. The uncertain natural course in individual patients hinders clinical trials of promising treatments. In this study, w...

    Authors: Rie Sasaki, Futaba Maki, Daisuke Hara, Shigeaki Tanaka and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2017 4:9

    Content type: Research

    Published on:

  4. Granule cell neuronopathy (GCN) is a rare disease caused by the JC virus, leading to degeneration of cerebellar granule cell neurons. Primarily described in patients with AIDS, it has also been diagnosed in pa...

    Authors: Kathryn B. Holroyd, Elias S. Sotirchos, Scott R. DeBoer, Kelly A. Mills and Scott D. Newsome

    Citation: Cerebellum & Ataxias 2017 4:8

    Content type: Case report

    Published on:

  5. Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant inherited neurodegenerative disorder. Several post-mortem and imaging studies have shown cerebellar and brainstem atroph...

    Authors: Carlos R. Hernandez-Castillo, Rosalinda Diaz, Aurelio Campos-Romo and Juan Fernandez-Ruiz

    Citation: Cerebellum & Ataxias 2017 4:7

    Content type: Research

    Published on:

  6. Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas...

    Authors: Matteo Bologna and Alfredo Berardelli

    Citation: Cerebellum & Ataxias 2017 4:6

    Content type: Review

    Published on:

  7. Progressive multifocal leukoencephalopathy (PML) is a demyelinating disorder of the central nervous system caused by reactivation of the JC-virus and is in most cases associated with underlying immunosuppressi...

    Authors: Ivan Kmezic, Jan Weinberg, Dan Hauzenberger, Farouk Hashim, Evangelia Kollia, Monika Klimkowska, Inger Nennesmo and Martin Paucar

    Citation: Cerebellum & Ataxias 2017 4:5

    Content type: Case report

    Published on:

  8. Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9. Due to epigenetic alteratio...

    Authors: Katrin Bürk

    Citation: Cerebellum & Ataxias 2017 4:4

    Content type: Review

    Published on:

  9. Cerebellar mutism syndrome (CMS) or posterior fossa syndrome (PFS) consists of a constellation of neuropsychiatric, neuropsychological and neurogenic speech and language deficits. It is most commonly observed ...

    Authors: E. De Witte, I. Wilssens, D. De Surgeloose, G. Dua, M. Moens, J. Verhoeven, M. Manto and P. Mariën

    Citation: Cerebellum & Ataxias 2017 4:2

    Content type: Case report

    Published on:

  10. Cerebellar ataxia with sensory ganglionopathy is a rare neurological combination that can occur in some hereditary ataxias including mitochondrial diseases and in gluten sensitivity. Individually each conditio...

    Authors: Panagiotis Zis, Dasappaiah Ganesh Rao, Bart E Wagner, Lucinda Nicholson-Goult, Nigel Hoggard and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2017 4:1

    Content type: Case report

    Published on:

  11. Alcohol-related cerebellar degeneration is one of the commonest acquired forms of cerebellar ataxia. The exact pathogenic mechanisms by which alcohol leads to cerebellar damage remain unknown. Possible autorea...

    Authors: Priya D. Shanmugarajah, Nigel Hoggard, Stuart Currie, Daniel P. Aeschlimann, Pascale C. Aeschlimann, Dermot C. Gleeson, Mohammed Karajeh, Nicola Woodroofe, Richard A. Grünewald and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2016 3:17

    Content type: Research

    Published on:

  12. Several studies have highlighted the therapeutic potential of transcranial direct current stimulation (tDCS) in patients with neurological diseases, including dementia, epilepsy, post-stroke dysfunctions, move...

    Authors: Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero and Alberto Priori

    Citation: Cerebellum & Ataxias 2016 3:16

    Content type: Review

    Published on:

  13. Low-frequency electrical stimulation to the motor cortex (LFSMC) depresses the excitability of motor circuits by long-term depression (LTD)-like effects. The interactions between LFSMC and cathodal direct curr...

    Authors: Nordeyn Oulad Ben Taib and Mario Manto

    Citation: Cerebellum & Ataxias 2016 3:15

    Content type: Research

    Published on:

  14. Progression of clinical symptoms and cerebellar atrophy may vary among subtypes of spinocerebellar degeneration and multiple system atrophy. The aim of this cross-sectional study was to demonstrate the relatio...

    Authors: Daisuke Hara, Futaba Maki, Shigeaki Tanaka, Rie Sasaki and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2016 3:14

    Content type: Research

    Published on:

  15. There exists a lack of consensus regarding how cerebellar over-activity might influence tremor in Parkinson’s disease (PD). Specifically, it is unclear whether resting or postural tremor are differentially aff...

    Authors: Shannon C. Lefaivre, Matt J. N. Brown and Quincy J. Almeida

    Citation: Cerebellum & Ataxias 2016 3:13

    Content type: Research

    Published on:

  16. Acetyl-DL-leucine is a modified amino acid that was observed to improve ataxic symptoms in patients with sporadic and hereditary forms of ataxia. Here, we investigated the effect of the treatment with Acetyl-D...

    Authors: Roman Schniepp, Michael Strupp, Max Wuehr, Klaus Jahn, Marianne Dieterich, Thomas Brandt and Katharina Feil

    Citation: Cerebellum & Ataxias 2016 3:8

    Content type: Letter to the Editor

    Published on:

  17. Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disorder that affects the cerebellar system and other subcortical regions of the brain. As for other cerebellar diseases, the severity of this type o...

    Authors: Irene Pulido-Valdeolivas, David Gómez-Andrés, Irene Sanz-Gallego, Estrella Rausell and Javier Arpa

    Citation: Cerebellum & Ataxias 2016 3:4

    Content type: Research

    Published on:

  18. Benign hereditary chorea is a rare disorder which is characterized by early onset, non-progressive choreic movement disturbance, with other hyperkinetic movements and unsteadiness also commonly seen. Hypothyro...

    Authors: Jeanette Koht, Sven Olav Løstegaard, Iselin Wedding, Marie Vidailhet, Malek Louha and Chantal ME Tallaksen

    Citation: Cerebellum & Ataxias 2016 3:3

    Content type: Case report

    Published on:

  19. Spinocerebellar ataxias (SСAs) are a highly heterogeneous group of inherited neurological disorders. The symptoms of ataxia vary in individual patients and even within the same SCA subtype. A study of a four-g...

    Authors: M. I. Shadrina, M. V. Shulskaya, S. A. Klyushnikov, T. Nikopensius, M. Nelis, P. A. Kivistik, A. A. Komar, S. A. Limborska, S. N. Illarioshkin and P. A. Slominsky

    Citation: Cerebellum & Ataxias 2016 3:2

    Content type: Research

    Published on:

  20. Cerebellar abnormalities are encountered in a high number of neurological diseases that present in the neonatal period. These disorders can be categorized broadly as inherited (e.g. malformations, inborn error...

    Authors: Jessica L. Klein, Monica E. Lemmon, Frances J. Northington, Eugen Boltshauser, Thierry A. G. M. Huisman and Andrea Poretti

    Citation: Cerebellum & Ataxias 2016 3:1

    Content type: Review

    Published on:

  21. Spinocerebellar ataxia type 28 (SCA28) is related to mutations of the ATPase family gene 3-like 2 gene (AFG3L2). To date, 13 private missense mutations have been identified in families of French, Italian, and Ger...

    Authors: Christine Zühlke, Barbara Mikat, Dagmar Timmann, Dagmar Wieczorek, Gabriele Gillessen-Kaesbach and Katrin Bürk

    Citation: Cerebellum & Ataxias 2015 2:19

    Content type: Research

    Published on:

  22. In the majority of right-handed subjects, language processing is subserved by a close interplay between the left cerebral hemisphere and right cerebellum. Within this network, the dominant fronto-insular regio...

    Authors: Kim van Dun, Elke De Witte, Wendy Van Daele, Wim Van Hecke, Mario Manto and Peter Mariën

    Citation: Cerebellum & Ataxias 2015 2:18

    Content type: Case report

    Published on:

  23. Mitochondrial disease can manifest as multi-organ disorder, often with neurological dysfunction. Cerebellar ataxia in isolation or in combination with other features can result from mitochondrial disease yet g...

    Authors: David Bargiela, Priya Shanmugarajah, Christine Lo, Emma L. Blakely, Robert W. Taylor, Rita Horvath, Stephen Wharton, Patrick F. Chinnery and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:16

    Content type: Research

    Published on:

  24. Crossed cerebello-cerebral diaschisis (CCCD) conventionally refers to decreased resting cerebral activity caused by injury to the contralateral cerebellum. We investigated whether functional activation of a co...

    Authors: Takayuki Nakahachi, Ryouhei Ishii, Leonides Canuet and Masao Iwase

    Citation: Cerebellum & Ataxias 2015 2:15

    Content type: Case Report

    Published on:

  25. Immune-mediated cerebellar ataxias include gluten ataxia, paraneoplastic cerebellar degeneration, GAD antibody associated cerebellar ataxia, and Hashimoto’s encephalopathy. Despite the identification of an inc...

    Authors: Hiroshi Mitoma, Marios Hadjivassiliou and Jérôme Honnorat

    Citation: Cerebellum & Ataxias 2015 2:14

    Content type: Review

    Published on:

  26. Following in the vein of studies that concluded that music training resulted in plastic changes in Einstein’s cerebral cortex, controlled research has shown that music training (1) enhances central executive a...

    Authors: Larry Vandervert

    Citation: Cerebellum & Ataxias 2015 2:11

    Content type: Review

    Published on:

  27. Until the end of 18th century, the role of the cerebellum remained obscure. The turning point occurred when Luigi Galvani showed that muscle contraction is due to electricity and Alessandro Volta produced the ...

    Authors: Marinella Coco and Vincenzo Perciavalle

    Citation: Cerebellum & Ataxias 2015 2:10

    Content type: Commentary

    Published on:

  28. The aim of this study was to investigate the usefulness of a triaxial accelerometer for the clinical assessment of standing and gait impairment in ataxic patients quantitatively. Fifty-one patients with spinoc...

    Authors: Akira Matsushima, Kunihiro Yoshida, Hirokazu Genno, Asuka Murata, Setsuko Matsuzawa, Katsuya Nakamura, Akinori Nakamura and Shu-ichi Ikeda

    Citation: Cerebellum & Ataxias 2015 2:9

    Content type: Research

    Published on:

  29. The cerebellum is important for motor control, cognition, and language processing. Afferent and efferent fibers are major components of cerebellar circuitry and impairment of these circuits causes severe cereb...

    Authors: Maryam Rahimi-Balaei, Pegah Afsharinezhad, Karen Bailey, Matthew Buchok, Behzad Yeganeh and Hassan Marzban

    Citation: Cerebellum & Ataxias 2015 2:7

    Content type: Review

    Published on:

  30. The cerebellum plays an important role for balance control and the coordination of voluntary movements. Beyond that there is growing evidence that the cerebellum is also involved in cognitive functions. How at...

    Authors: Heike Jacobi, Juliane Alfes, Martina Minnerop, Jürgen Konczak, Thomas Klockgether and Dagmar Timmann

    Citation: Cerebellum & Ataxias 2015 2:6

    Content type: Research

    Published on:

  31. We report a mother and daughter with autosomal recessive ataxia with occulomotor apraxia in whom sequence analysis of senataxin revealed a dignosis of AOA2 (ataxia with occulomotor apraxia type 2) in both indi...

    Authors: Laurence Newrick, Malcolm Taylor and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:5

    Content type: Case report

    Published on:

  32. A 50-year-old man presented with a brief history of slurred speech, unsteadiness, double vision and paraesthesia. He had been unwell for 12 days with campylobacter gastroenteritis. On examination, there was op...

    Authors: Robert D Sandler, Nigel Hoggard and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2015 2:3

    Content type: Commentary

    Published on:

  33. Spinocerebellar Ataxia Type 3/Machado-Joseph Disease (SCA3/MJD) is a hereditary neurodegenerative disorder resulting from the expansion of CAG repeats in the ATXN3 gene. It is the most common autosomal dominant a...

    Authors: Yanetza González-Zaldívar, Yaimeé Vázquez-Mojena, José M Laffita-Mesa, Luis E Almaguer-Mederos, Roberto Rodríguez-Labrada, Gilberto Sánchez-Cruz, Raúl Aguilera-Rodríguez, Tania Cruz-Mariño, Nalia Canales-Ochoa, Patrick MacLeod and Luis Velázquez-Pérez

    Citation: Cerebellum & Ataxias 2015 2:1

    Content type: Research

    Published on: