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Review
The cerebellum is a vulnerable target of autoimmunity in the CNS. The category of immune-mediated cerebellar ataxias (IMCAs) was recently established, and includes in particular paraneoplastic cerebellar degen...
Cerebellum & Ataxias 2017 4:16
Published on: 21 September 2017
Research
The control of grip forces when moving a hand held object is impaired in patients with cerebellar degeneration. We asked the question whether after-effects of anodal transcranial direct current stimulation (tD...
Cerebellum & Ataxias 2017 4:15
Published on: 15 September 2017
Case report
Hemicerebellitisis a rare acquired condition, typical of the pediatric age. A residual switched handedness may develop after remission of acute cerebellar symptoms.
Cerebellum & Ataxias 2017 4:14
Published on: 14 September 2017
Research
Damage to the cerebellum may lead to motor dysfunctions, but also to the neuropsychological deficits that comprise the Cerebellar Cognitive Affective Syndrome (CCAS). It can affect executive functions, attenti...
Cerebellum & Ataxias 2017 4:13
Published on: 28 July 2017
Research
Mathematicians and scientists have struggled to adequately describe the ultimate foundations of mathematics. Nobel laureates Albert Einstein and Eugene Wigner were perplexed by this issue, with Wigner concluding ...
Cerebellum & Ataxias 2017 4:12
Published on: 20 July 2017
Research
Multiple system atrophy (MSA) is a rare progressive neurodegenerative disorder for which brief yet sensitive scale is required in order for use in clinical trials and general screening. We previously compared ...
Cerebellum & Ataxias 2017 4:11
Published on: 3 July 2017
Research
The pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cereb...
Cerebellum & Ataxias 2017 4:10
Published on: 3 July 2017
Research
The rate of disease progression differs among patients with degenerative cerebellar ataxia. The uncertain natural course in individual patients hinders clinical trials of promising treatments. In this study, w...
Cerebellum & Ataxias 2017 4:9
Published on: 29 June 2017
Case report
Granule cell neuronopathy (GCN) is a rare disease caused by the JC virus, leading to degeneration of cerebellar granule cell neurons. Primarily described in patients with AIDS, it has also been diagnosed in pa...
Cerebellum & Ataxias 2017 4:8
Published on: 23 June 2017
Research
Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant inherited neurodegenerative disorder. Several post-mortem and imaging studies have shown cerebellar and brainstem atroph...
Cerebellum & Ataxias 2017 4:7
Published on: 6 June 2017
Review
Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas...
Cerebellum & Ataxias 2017 4:6
Published on: 12 May 2017
Case report
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disorder of the central nervous system caused by reactivation of the JC-virus and is in most cases associated with underlying immunosuppressi...
Cerebellum & Ataxias 2017 4:5
Published on: 21 April 2017
Review
Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9. Due to epigenetic alteratio...
Cerebellum & Ataxias 2017 4:4
Published on: 7 April 2017
Review
The classification of autosomal recessive ataxias represents a significant challenge because of high genetic heterogeneity and complex phenotypes. We conducted a comprehensive systematic review of the literatu...
Cerebellum & Ataxias 2017 4:3
Published on: 23 February 2017
Case report
Cerebellar mutism syndrome (CMS) or posterior fossa syndrome (PFS) consists of a constellation of neuropsychiatric, neuropsychological and neurogenic speech and language deficits. It is most commonly observed ...
Cerebellum & Ataxias 2017 4:2
Published on: 6 January 2017
Case report
Cerebellar ataxia with sensory ganglionopathy is a rare neurological combination that can occur in some hereditary ataxias including mitochondrial diseases and in gluten sensitivity. Individually each conditio...
Cerebellum & Ataxias 2017 4:1
Published on: 5 January 2017
Review
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder that primarily affects the cerebellum and brainstem. The genetic mutation is an expansion of CAG trinucleotide repeats w...
Cerebellum & Ataxias 2016 3:20
Published on: 22 November 2016
Review
The recent development of non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) has allowed the non-invasive assessment of cerebellar function in humans. Early studies showe...
Cerebellum & Ataxias 2016 3:19
Published on: 16 November 2016
Case report
Cerebellar ataxia represents a rare and severe complication of Sjӧgren syndrome (SS), especially with a progressive onset and cerebellar atrophy on imaging.
Cerebellum & Ataxias 2016 3:18
Published on: 19 October 2016
Research
Alcohol-related cerebellar degeneration is one of the commonest acquired forms of cerebellar ataxia. The exact pathogenic mechanisms by which alcohol leads to cerebellar damage remain unknown. Possible autorea...
Cerebellum & Ataxias 2016 3:17
Published on: 3 October 2016
Review
Several studies have highlighted the therapeutic potential of transcranial direct current stimulation (tDCS) in patients with neurological diseases, including dementia, epilepsy, post-stroke dysfunctions, move...
Cerebellum & Ataxias 2016 3:16
Published on: 2 September 2016
Research
Low-frequency electrical stimulation to the motor cortex (LFSMC) depresses the excitability of motor circuits by long-term depression (LTD)-like effects. The interactions between LFSMC and cathodal direct curr...
Cerebellum & Ataxias 2016 3:15
Published on: 30 August 2016
Research
Progression of clinical symptoms and cerebellar atrophy may vary among subtypes of spinocerebellar degeneration and multiple system atrophy. The aim of this cross-sectional study was to demonstrate the relatio...
Cerebellum & Ataxias 2016 3:14
Published on: 17 August 2016
Research
There exists a lack of consensus regarding how cerebellar over-activity might influence tremor in Parkinson’s disease (PD). Specifically, it is unclear whether resting or postural tremor are differentially aff...
Cerebellum & Ataxias 2016 3:13
Published on: 8 June 2016
Research
The objective of the present study was an investigation of root Rubia Tinctorum (Madder) as a natural dye to identification of granular layer interneurons of the rat cerebellum.
Cerebellum & Ataxias 2016 3:12
Published on: 2 June 2016
