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  1. Content type: Case report

    Mutations in the Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1) gene cause spinocerebellar ataxia type 29 (SCA29), a rare congenital-onset autosomal dominant non-progressive cerebellar ataxia. The Māori, in...

    Authors: Kathie J. Ngo, Gemma Poke, Katherine Neas and Brent L. Fogel

    Citation: Cerebellum & Ataxias 2019 6:14

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  2. Content type: Review

    Nonmotor symptoms (NMS) have been increasingly recognized in a number of neurodegenerative diseases with a burden of disability that parallels or even surpasses that induced by motor symptoms. As NMS have ofte...

    Authors: Adriana Moro, Mariana Moscovich, Marina Farah, Carlos Henrique F. Camargo, Hélio A. G. Teive and Renato P. Munhoz

    Citation: Cerebellum & Ataxias 2019 6:12

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  3. Content type: Review

    Disorders of the cerebellum may present with motor, cognitive, behavioral and affective symptoms. There is a growing interest in developing neuroanatomical models of symptoms generation that involve the cerebe...

    Authors: Emanuela Molinari, Maria Oto, Ashita Waterston and Natasha Fullerton

    Citation: Cerebellum & Ataxias 2019 6:11

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  4. Content type: Research

    Friedreich ataxia (FRDA) is the most common familial ataxia syndrome in Central and Southern Europe but rare in Scandinavia. Biallelic mutations in SH3 domain and tetratricopeptide repeats 2 (SH3TC2) cause Charco...

    Authors: Humberto Skott, Cristina Muntean-Firanescu, Kristin Samuelsson, Luca Verrecchia, Per Svenningsson, Helena Malmgren, Carmen Cananau, Alberto J. Espay, Rayomand Press, Göran Solders and Martin Paucar

    Citation: Cerebellum & Ataxias 2019 6:9

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  5. Content type: Case report

    Paraneoplastic cerebellar degeneration is usually associated with gynecological and breast cancer, lung cancer, and Hodgkin’s lymphoma. Renal cell carcinoma has rarely been described as an underlying malignanc...

    Authors: Sara M. Souza, Barbara O. Santos, Isadora C.A. Sodré, Ana Luiza P. Oliveira, Diogo Terrana and Mariana Spitz

    Citation: Cerebellum & Ataxias 2019 6:8

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  6. Content type: Research

    Multiple system atrophy (MSA) is a sporadic adult-onset neurodegenerative disease with a cerebellar subtype where ataxic symptoms predominate (MSA-C) associated with autonomic dysfunction and a grave prognosis...

    Authors: Viren H. Kadodwala, Marios Hadjivassiliou, Stuart Currie, Nicholas Skipper and Nigel Hoggard

    Citation: Cerebellum & Ataxias 2019 6:7

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  7. Content type: Research

    Within the context of Clausi, Olivito, Lupo, Siciliano, Bozzali and Leggio’s (Cell Neurosci 12:510, 2019) insightful study of how prediction of theory of mind (ToM) is compromised in degenerative cerebellar at...

    Authors: Larry Vandervert

    Citation: Cerebellum & Ataxias 2019 6:6

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    The Publisher Correction to this article has been published in Cerebellum & Ataxias 2019 6:10

  8. Content type: Case report

    Tremor is a common side effect of treatment with lithium. Its characteristics can vary and when less rhythmical, distinction from myoclonus can be difficult.

    Authors: Ptolemaios Georgios Sarrigiannis, Panagiotis Zis, Zoe Charlotte Unwin, Daniel J. Blackburn, Nigel Hoggard, Yifan Zhao, Stephen A. Billings, Aijaz A. Khan, John Yianni and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2019 6:5

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  9. Content type: Case report

    Fetal magnetic resonance imaging (MRI), mainly performed at standard field strength, plays a role in the classification of posterior fossa malformations. In the context of early second-trimester screening, upw...

    Authors: Thomas Kau, Robert Birnbacher, Peter Schwärzler, Sandra Habernig, Hannes Deutschmann and Eugen Boltshauser

    Citation: Cerebellum & Ataxias 2019 6:4

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  10. Content type: Research

    Cognitive decline is a common non-motor feature characterizing Spinocerebellar Ataxia type 2 (SCA2) during the prodromal stage, nevertheless a reduced number of surrogate biomarkers of these alterations have b...

    Authors: Roberto Rodríguez-Labrada, Luis Velázquez-Pérez, Ricardo Ortega-Sánchez, Arnoy Peña-Acosta, Yaimeé Vázquez-Mojena, Nalia Canales-Ochoa, Jacqueline Medrano-Montero, Reidenis Torres-Vega and Yanetza González-Zaldivar

    Citation: Cerebellum & Ataxias 2019 6:3

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  11. Content type: Case report

    CAPOS (Cerebellar ataxia, Areflexia, Pes cavus, Optic atrophy and Sensorineural hearing loss) syndrome is caused by the heterozygous mutation, c.2452G > A, in the ATP1A3 gene. Other mutations in this gene can cau...

    Authors: Ida Stenshorne, Magnhild Rasmussen, Panagiotis Salvanos, Chantal M. E. Tallaksen, Laurence A. Bindoff and Jeanette Koht

    Citation: Cerebellum & Ataxias 2019 6:2

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  12. Content type: Review

    Eye movements are frequently considered diagnostic markers indicating involvement of the cerebellum. Impaired amplitude of saccades (saccade dysmetria), impaired gaze holding function (horizontal or downbeat n...

    Authors: Kelsey Jensen, Sinem Balta Beylergil and Aasef G. Shaikh

    Citation: Cerebellum & Ataxias 2019 6:1

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  13. Content type: Case report

    In Patients with spinocerebellar ataxia type 6 (SCA6) are often treated by transcranial magnetic stimulation (TMS) over the motor cortex and cerebellum. However, few reports have examined effective therapeutic...

    Authors: Kentaro Kawamura, Seiji Etoh and Megumi Shimodozono

    Citation: Cerebellum & Ataxias 2018 5:15

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  14. Content type: Research

    Many children with neurofibromatosis type 1 (NF1) have focal abnormal signal intensities (FASI) on brain MRI, whose full clinical impact and natural history have not been studied systematically. Our aims are t...

    Authors: Michael S Salman, Shakhawat Hossain, Lina Alqublan, Martin Bunge and Katya Rozovsky

    Citation: Cerebellum & Ataxias 2018 5:14

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  15. Content type: Research

    Focal abnormal signal intensities (FASI) on brain MRI occur commonly in patients with neurofibromatosis type 1 (NF1). The natural history of cerebellar FASI and their correlation with clinical features have no...

    Authors: Michael S. Salman, Shakhawat Hossain, Samantha Gorun, Lina Alqublan, Martin Bunge and Katya Rozovsky

    Citation: Cerebellum & Ataxias 2018 5:13

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  16. Content type: Correction

    After publication of the original article [1], the authors reported their Given Names and Family names had been incorrectly reverted so they were presented as:

    Authors: Stephen Ramanoel, Elizabeth York and Christophe Habas

    Citation: Cerebellum & Ataxias 2018 5:10

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    The original article was published in Cerebellum & Ataxias 2018 5:9

  17. Content type: Review

    The cerebellum has a striking homogeneous cytoarchitecture and participates in both motor and non-motor domains. Indeed, a wealth of evidence from neuroanatomical, electrophysiological, neuroimaging and clinic...

    Authors: Charlotte Lawrenson, Martin Bares, Anita Kamondi, Andrea Kovács, Bridget Lumb, Richard Apps, Pavel Filip and Mario Manto

    Citation: Cerebellum & Ataxias 2018 5:8

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  18. Content type: Research

    Joubert syndrome (JS) is a rare, autosomal recessively inherited genetic disorder characterized morphologically by unique developmental malformations of the cerebellum and brainstem (the molar tooth sign), and...

    Authors: Chelsea L. Hickey, Janet C. Sherman, Paula Goldenberg, Amy Kritzer, Paul Caruso, Jeremy D. Schmahmann and Mary K. Colvin

    Citation: Cerebellum & Ataxias 2018 5:5

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  19. Content type: Case report

    Spinocerebellar ataxia 17 (SCA17) is one of the most heterogeneous forms of autosomal dominant cerebellar ataxias with a large clinical spectrum which can mimic other movement disorders such as Huntington dise...

    Authors: Paola Origone, Fabio Gotta, Merit Lamp, Lucia Trevisan, Alessandro Geroldi, Davide Massucco, Matteo Grazzini, Federico Massa, Flavia Ticconi, Matteo Bauckneht, Roberta Marchese, Giovanni Abbruzzese, Emilia Bellone and Paola Mandich

    Citation: Cerebellum & Ataxias 2018 5:7

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  20. Content type: Case report

    Cranial-nerve non-invasive neuromodulation (CN-NINM) using the portable neuromodulation stimulator (PoNS™) device has been proposed as a novel adjuvant intervention to improve efficacy of gait and balance. This d...

    Authors: Andisheh Bastani, L. Eduardo Cofré Lizama, Maryam Zoghi, Grant Blashki, Stephen Davis, Andrew H. Kaye, Fary Khan and Mary P. Galea

    Citation: Cerebellum & Ataxias 2018 5:6

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  21. Content type: Research

    Autism is a neurodevelopmental disorder that is first manifested during early childhood. Postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mGluR5) i...

    Authors: S. Hossein Fatemi, Dean F. Wong, James R. Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D. Folsom, Suma Jacob, George M. Realmuto, José V. Pardo and Susanne Lee

    Citation: Cerebellum & Ataxias 2018 5:3

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  22. Content type: Case Report

    In traditional models of essential tremor, the inferior olivary nucleus was posited to play a central role as the pacemaker for the tremor. However, recent data call this disease model into question.

    Authors: Elan D. Louis, Daniel Trujillo Diaz, Sheng-Han Kuo, Shi-Rui Gan, Etty P. Cortes, Jean Paul G. Vonsattel and Phyllis L. Faust

    Citation: Cerebellum & Ataxias 2018 5:1

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  23. Content type: Editorial

    The feasibility to administer magnetic and electric fields in a non-invasive manner to influence brain areas has attracted scientists interested in studying the neural correlates of normal and pathological for...

    Authors: Adriana B. Conforto and Dennis J. L. G. Schutter

    Citation: Cerebellum & Ataxias 2017 4:21

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  24. Content type: Research

    Cerebellar ataxia with sensory ganglionopathy (SG) is a disabling combination of neurological dysfunction usually seen as part of some hereditary ataxias. However, patients may present with this combination wi...

    Authors: Panagiotis Zis, Ptolemaios Georgios Sarrigiannis, Dasappaiah Ganesh Rao, Nigel Hoggard, David Surendran Sanders and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2017 4:20

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  25. Content type: Research

    Saccade slowing has been proposed as endophenotype marker in Spinocerebellar Ataxia type 2 (SCA2), nevertheless the heritability of this trait has not been properly demonstrated. Thus the present paper was aim...

    Authors: Roberto Rodríguez-Labrada, Yaimeé Vázquez-Mojena, Nalia Canales-Ochoa, Jacqueline Medrano-Montero and Luis Velázquez-Pérez

    Citation: Cerebellum & Ataxias 2017 4:19

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  26. Content type: Research

    To date, 43 types of Spinocerebellar Ataxias (SCAs) have been identified. A subset of the SCAs are caused by the pathogenic expansion of a CAG repeat tract within the corresponding gene. Ethnic and geographic ...

    Authors: Masharip Atadzhanov, Danielle C. Smith, Mwila H. Mwaba, Omar K. Siddiqi, Alan Bryer and L. Jacquie Greenberg

    Citation: Cerebellum & Ataxias 2017 4:17

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  27. Content type: Review

    The cerebellum is a vulnerable target of autoimmunity in the CNS. The category of immune-mediated cerebellar ataxias (IMCAs) was recently established, and includes in particular paraneoplastic cerebellar degen...

    Authors: Hiroshi Mitoma, Mario Manto and Christiane S. Hampe

    Citation: Cerebellum & Ataxias 2017 4:16

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  28. Content type: Research

    The control of grip forces when moving a hand held object is impaired in patients with cerebellar degeneration. We asked the question whether after-effects of anodal transcranial direct current stimulation (tD...

    Authors: Liane John, Michael Küper, Thomas Hulst, Dagmar Timmann and Joachim Hermsdörfer

    Citation: Cerebellum & Ataxias 2017 4:15

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  29. Content type: Case report

    Hemicerebellitisis a rare acquired condition, typical of the pediatric age. A residual switched handedness may develop after remission of acute cerebellar symptoms.

    Authors: Mario Mascalchi, Matteo Lenge, Andrea Bianchi, Emanuele Bartolini, Gioele Gavazzi, Flavio Giordano and Renzo Guerrini

    Citation: Cerebellum & Ataxias 2017 4:14

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  30. Content type: Research

    Damage to the cerebellum may lead to motor dysfunctions, but also to the neuropsychological deficits that comprise the Cerebellar Cognitive Affective Syndrome (CCAS). It can affect executive functions, attenti...

    Authors: Eva Bolceková, Matej Mojzeš, Quang Van Tran, Jaromír Kukal, Svatopluk Ostrý, Petr Kulišťák and Robert Rusina

    Citation: Cerebellum & Ataxias 2017 4:13

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  31. Content type: Research

    Multiple system atrophy (MSA) is a rare progressive neurodegenerative disorder for which brief yet sensitive scale is required in order for use in clinical trials and general screening. We previously compared ...

    Authors: Masaaki Matsushima, Ichiro Yabe, Ikuko Takahashi, Makoto Hirotani, Takahiro Kano, Kazuhiro Horiuchi, Hideki Houzen and Hidenao Sasaki

    Citation: Cerebellum & Ataxias 2017 4:11

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  32. Content type: Research

    The pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cereb...

    Authors: Jonathan P. Dyke, Eric Cameron, Nora Hernandez, Ulrike Dydak and Elan D. Louis

    Citation: Cerebellum & Ataxias 2017 4:10

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  33. Content type: Research

    The rate of disease progression differs among patients with degenerative cerebellar ataxia. The uncertain natural course in individual patients hinders clinical trials of promising treatments. In this study, w...

    Authors: Rie Sasaki, Futaba Maki, Daisuke Hara, Shigeaki Tanaka and Yasuhiro Hasegawa

    Citation: Cerebellum & Ataxias 2017 4:9

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  34. Content type: Case report

    Granule cell neuronopathy (GCN) is a rare disease caused by the JC virus, leading to degeneration of cerebellar granule cell neurons. Primarily described in patients with AIDS, it has also been diagnosed in pa...

    Authors: Kathryn B. Holroyd, Elias S. Sotirchos, Scott R. DeBoer, Kelly A. Mills and Scott D. Newsome

    Citation: Cerebellum & Ataxias 2017 4:8

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  35. Content type: Research

    Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant inherited neurodegenerative disorder. Several post-mortem and imaging studies have shown cerebellar and brainstem atroph...

    Authors: Carlos R. Hernandez-Castillo, Rosalinda Diaz, Aurelio Campos-Romo and Juan Fernandez-Ruiz

    Citation: Cerebellum & Ataxias 2017 4:7

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  36. Content type: Review

    Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas...

    Authors: Matteo Bologna and Alfredo Berardelli

    Citation: Cerebellum & Ataxias 2017 4:6

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  37. Content type: Case report

    Progressive multifocal leukoencephalopathy (PML) is a demyelinating disorder of the central nervous system caused by reactivation of the JC-virus and is in most cases associated with underlying immunosuppressi...

    Authors: Ivan Kmezic, Jan Weinberg, Dan Hauzenberger, Farouk Hashim, Evangelia Kollia, Monika Klimkowska, Inger Nennesmo and Martin Paucar

    Citation: Cerebellum & Ataxias 2017 4:5

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  38. Content type: Review

    Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9. Due to epigenetic alteratio...

    Authors: Katrin Bürk

    Citation: Cerebellum & Ataxias 2017 4:4

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  39. Content type: Case report

    Cerebellar mutism syndrome (CMS) or posterior fossa syndrome (PFS) consists of a constellation of neuropsychiatric, neuropsychological and neurogenic speech and language deficits. It is most commonly observed ...

    Authors: E. De Witte, I. Wilssens, D. De Surgeloose, G. Dua, M. Moens, J. Verhoeven, M. Manto and P. Mariën

    Citation: Cerebellum & Ataxias 2017 4:2

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  40. Content type: Case report

    Cerebellar ataxia with sensory ganglionopathy is a rare neurological combination that can occur in some hereditary ataxias including mitochondrial diseases and in gluten sensitivity. Individually each conditio...

    Authors: Panagiotis Zis, Dasappaiah Ganesh Rao, Bart E Wagner, Lucinda Nicholson-Goult, Nigel Hoggard and Marios Hadjivassiliou

    Citation: Cerebellum & Ataxias 2017 4:1

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